[Incidence of occult lumbro-sacral spina bifida in parents of children with spina bifida (concerning 80 pairs of parents with affected children)].
2
Citation
0
Reference
10
Related Paper
Citation Trend
Abstract:
Authors examined 80 pairs of parents with affected children with spina-bifida. They compared the incidence of spina-bifida occulta in parents and in 211 controls. The conclusion is: there is no increased incidence of spina-bifida occulta in parents of spina-bifida.Keywords:
Spina bifida occulta
Occult
Cite
The terms "occult meningocele" and "spina bifida occulta" have occasioned confusion in the past. Kaufmann implies that these are more or less synonymous. Adami, however, considers "meningocele" to be a cyst of the meninges, or a hernia, projecting through the walls of the vertebral canal, and "spina bifida occulta" to be a localized lack of junction of the laminae with no projecting fluid sac. In this paper the term "occult meningocele" is employed rather than the often used "spina bifida occulta." It embraces a diffuse dilatation of the dural sac with or without the relatively inconsequential element of herniation into the soft tissues. The meningocele, rather than the bifid spinous process, is the significant element. In one of the three cases upon which this report is based there was no spina bifida. Mixter (1), in his section in Lewis' "Practice of Surgery," gives an excellent description of this condition, using the term "spina bifida occulta." He describes it as a congenital malformation consisting of a defect in the closure of the vertebral arch, usually with an associated defect of the meninges and nerve tissues. He also states that, although there is no external meningeal sac, there is frequently a localized growth of hair. This was not present in any of our three cases. Mixter also adds that there is almost invariably a congenital lipoma either just beneath the skin or in some of the deeper structures. This was not true of our single operative case. In this same article the anatomical and pathological basis for the usual symptomatology is presented, and to this presentation the reader is referred for greater detail. In brief, Mixter describes one defect which is almost constant, the fusion of the central portion of the cauda equina into a single irregular bundle, which may be the site of various pathological processes comprising the nerve roots and causing disturbance of function. He mentions lipomata, dermoid cysts, and a band of dense connective tissue. Mixter also states that there are two types of history: one in which paralysis has been present since birth and one in which symptoms came on in later life. In one of our cases, the symptoms were precipitated in middle life by an injury which evidently affected the thin bony shell over the sac (Case III). The usual striking symptom is lack of bladder control, present in two of our cases, absent in the third. Occasionally, there are toe drop and a saddle anesthesia. Enderle (2), in 1932, demonstrated an occult intrasacral meningocele by myelography, which he thought was the first to be described in the roentgen literature. The patient was a forty-seven-year-old woman with pain radiating down the posterior surfaces of both legs. Plain films showed a large sacral hiatus and lumbarization of S-1. A normal cul-de-sac was demonstrated on immediate examination. Twenty-four hours later the oil descended into a lower sac, 7 × 4 × 2 cm., which was united to the lumbar sac by a narrow isthmus.
Spina bifida occulta
Meninges
Occult
Cite
Citations (17)
Spina bifida occulta
Cite
Citations (1)
COWELL, MARY J.; COWELL, HENRY R. M.D.Editor(s): URIST, MARSHALL R. M.D. Author Information
Spina bifida occulta
Cite
Citations (2)
Occult spinal dysraphism (OSD) refers to a diverse group of congenital abnormalities resulting from varying degrees of disordered neuro-embryogenesis. Several terms have been used to describe these conditions, including spina bifida occulta and closed neural tube defects.
Spina bifida occulta
Spinal dysraphism
Occult
Neural tube defect
Cite
Citations (4)
Occult
Etiology
Tethered Cord
Spina bifida occulta
Encephalocele
Cite
Citations (17)
Summary. A radiological survey of 1204 members of the population of Bursa revealed a high prevalence of spina bifida occulta (16.3%). Hospital deliveries in the area also showed a high incidence of anencephalus and spina bifida aperta (5.8 per 1000 total births) in the years 1983 to 1986. In the first 6 months of 1987, however, there was an increase in incidence to 20 per 1000 births (P<0.01). The possibility is raised that the Chernobyl disaster of May 1986 might have resulted in the elevation of the rate in an already susceptible population.
Cite
Citations (43)
Spina bifida occulta
Spinal dysraphism
Occult
Meninges
Cite
Citations (1)
Occult
Neural tube defect
Encephalocele
Spina bifida occulta
Cite
Citations (82)
Non-metrical variants of the human cranium have been studied in 186 London crania of known age, sex and date of birth. The incidence of several variants was different in the two sexes, and these results were compared with those of other workers from different parts of the world. Few variants persistently favoured one sex: the majority behaved inconsistently. Age dependency was only demonstrated for one variant, while year of birth, presence of rickets, and spina bifida occulta, showed negligible influence on variant incidence. 20% of vertebral columns examined included an anomalous vertebra, usually sacral spina bifida occulta. Although family studies were largely inconclusive, this investigation provides no reason to doubt the basic genetical control of these variants.
Spina bifida occulta
Crania
Vertebra
Cite
Citations (207)
Authors examined 80 pairs of parents with affected children with spina-bifida. They compared the incidence of spina-bifida occulta in parents and in 211 controls. The conclusion is: there is no increased incidence of spina-bifida occulta in parents of spina-bifida.
Spina bifida occulta
Occult
Cite
Citations (2)