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    Esophageal Carcinoma-A Survey of Populations at Risk
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    Abstract:
    Carcinoma of the esophagus is found more commonly in association with head and neck tumors, lye stricture, achalasia, and Barrett esophagus than in the general population. Our experience with these associated entities in a population of 680 patients with carcinoma of the esophagus is reviewed. Carcinoma of the esophagus has traditionally had a very poor prognosis which continues to the present. Routine periodic use of double contrast esophagography is advocated to screen populations containing these associated high-risk entities. This may ultimately increase survival through diagnosis of earlier stages of carcinoma of the esophagus.
    A case of achalasia associated with squamous cell carcinoma of the esophagus is presented. Microscopic examination of the resected esophagus demonstrated abundant nerve fibers but absent ganglion cells throughout the tumor-involved segment. This finding is believed to be the cause of achalasia in this patient.
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    Objective To explore the changes of serum SIL 2R in patients with carcinoma of esophagus perioperatively.Methods The serum SIL 2R level was measured by Samdiwich ELISA in 38 patients with carcinoma of esophagus and 35 normal controls.Results Postoperative serum SIL 2R level in patients with carcinoma of esophagus was significant higher than that in normal controls( P 0.01).Postoperative follow up for 6 months the SIL 2R level was continuous higher in the patients with recurrence and SIL 2R level returned to normal in the patiants without recurrence.Conclusion There is a close correlation between immune function and the development and prognosis of carcinoma of esophagus.
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    This paper describes 3 cases of esophageal carcinoma associated with achalasia, as well as 330 cases of esophageal carcinoma and 10 operated on for achalasia during the recent 8 years, in which clinical findings were comparatively investigated among the three disease groups. In the 3 cases of carcinoma associated with achalasia, female sex was predominant like in achalasia. The average age was 61 likewise in esophageal carcinoma. An average length of these tumors measured on the esophagogram was 9cm, i.e. larger than in esophageal carcinoma. Most tumors were located in the upper third of the thoracic esophagus. All cases were fairly advanced (stage IV). In two cases palliative resction was performed and one underwent no surgery. The prognoses of these cases were extremely poor, therefore we have realized that early detection of carcinoma is very important in patients with achalasia of the esophagus.
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    OBJECTIVE To investigate the effect of automatic compression system apply to postoperative patients with carcinoma of esophagus. METHODS A total of 82 postoperative patients with carcinoma of esophagus were randomly divided into the experimental group and the control group.To investigate the effect of postoperative patients with carcinoma of esophagus. RESULTS The difference between the two groups was statistically significant. CONCLUSION This showed that automatic compression system was helpful to reduce the discomfort of postoperative patients with carcinoma of esophagus.
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    Objective To summarize epidemiological feature,pathological characteristics and diagnosis with 742 cases carcinoma of esophagus.Methods Retrospectively analyse endoscopic and pathological interrelated information of 742 cases carcinoma of esophagus within past 5 years.Results Numerical statement of 742 cases carcinoma of esophagus in this study,the numbers of male patients and female patients are respectively 545 and 197(the proportion of male with female is 2.77∶1).The case numbers of the carcinoma at the upper part,the middle part,the lower part of esophagus are respectively 98,478,166.The case numbers of squamous cell carcinoma,adenocarcinoma,small cell carcinoma are respectively 725,15,2.Conclusion In recent years,the number of the patients that suffer carcinoma of esophagus is increasing,a large proportion of the patients are male and the diseased age of the patients is older.The squamous cell carcinoma is absolutely predominant in pathology.It can improve the early diagnosis of the carcinoma of esophagus that enhancing general survey and esophagoscope examining in high risk group.
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    Carcinoma of the esophagus is found more commonly in association with head and neck tumors, lye stricture, achalasia, and Barrett esophagus than in the general population. Our experience with these associated entities in a population of 680 patients with carcinoma of the esophagus is reviewed. Carcinoma of the esophagus has traditionally had a very poor prognosis which continues to the present. Routine periodic use of double contrast esophagography is advocated to screen populations containing these associated high-risk entities. This may ultimately increase survival through diagnosis of earlier stages of carcinoma of the esophagus.
    Objective To improve the diagnosis and treatment of achalasia accompanied with carcinomas of esophagus and cardia. Methods To retrospect the diagnosis, treatment and pathology of 12 cases of achalasia accompanied with carcinomas of esophagus and cardia. Results Of 12 cases achalasia accompanied with esophageal carcinoma or cardiac carcinoma , 4 cases were operated , and 2 cases survived more than 3 year , one case died in half a year of operation. one operated case was followed up less than half-one year. 6 cases treated with chemotherapy and radiotherapy survived from half a year to 1.5 year.Conclusion 1. The symptoms of esophageal carcinoma and cardiac carcinoma can be defied by the symptom of achalasia. 2. The incidence of esophageal cancer and cardiac cancer of patients with achalasia can not reduced after Heller operation. The patients with achalasia should be followed up regularly once a year . 3. The incidence of esophageal carcinoma of achalasia was higher. The patients of achalasia are the high-risk group. 4. When having special symptoms, post-operation patients should be counterchecked to be found early. 5. The incidence of esophageal carcinoma and cardiac carcinoma of patients with achalasia currently is similar with that of asynchronous carcinoma occurring. The patients of achalasia should be examined conventionally by esophagoscope in order to exclude the possibility of carcinomas of esophagus and cardia.
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    Serum CEA levels were determined serially by the Hansen Z gel technique on 41 patients with carcinoma of the esophagus and compared to 276 controls.Seventy percent of patients with carcinomas of the esophagus had elevated CEA levels.CEA levels greater than 10.0 ng/ml after therapy correlated with significantly shortened survival.CEA appears promising as an indicator of tumor presence in patients with carcinoma of the esophagus.