[Acute childhood gastroenteritis study at Central University Hospital of Pointe-à-Pitre/Abymes, Guadeloupe, from November 1997 to March 1998].
2
Citation
0
Reference
10
Related Paper
Abstract:
To determine the role of enteric pathogens in acute childhood diarrhoea in Guadeloupe, 161 children (108 cases and 53 controls) from 0 to 2 years of age, admitted to Pointe-à-Pitre/Abymes University Hospital, were evaluated over a five-month period. A known enteric pathogen was identified in 40.8% of children. The most commonly identified aetiologic agents were Salmonella (16.7% of cases), especially Haddar serotype and Rotavirus (20.5%). This virus was isolated more often in the dry season. Adenovirus were detected in 3.6% of diarrhoeal stools and were not significatively associated with diarrhoeal disease. No Shigella, Campylobacter or parasites were found.Keywords:
Diarrhoeal disease
Acute gastroenteritis
Cite
Journal Article Case-Control Study of Endemic Diarrheal Disease in Thai Children Get access Peter Echeverria, Peter Echeverria Please address requests for reprints to Dr. Peter Echeverria, Armed Forces Research Institute of Medical Sciences, APO San Francisco, California 96346-5000. Search for other works by this author on: Oxford Academic PubMed Google Scholar David N. Taylor, David N. Taylor Search for other works by this author on: Oxford Academic PubMed Google Scholar Udom Lexsomboon, Udom Lexsomboon Search for other works by this author on: Oxford Academic PubMed Google Scholar Manoon Bhaibulaya, Manoon Bhaibulaya Search for other works by this author on: Oxford Academic PubMed Google Scholar Neil R. Blacklow, Neil R. Blacklow Search for other works by this author on: Oxford Academic PubMed Google Scholar Kazumichi Tamura, Kazumichi Tamura Search for other works by this author on: Oxford Academic PubMed Google Scholar Riichi Sakazaki Riichi Sakazaki Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 159, Issue 3, March 1989, Pages 543–548, https://doi.org/10.1093/infdis/159.3.543 Published: 01 March 1989 Article history Received: 23 May 1988 Revision received: 13 September 1988 Published: 01 March 1989
Enterotoxigenic Escherichia coli
Enteropathogenic Escherichia coli
Diarrheal diseases
Cite
Citations (120)
Between March and July, 1987, faecal specimens from 371 diarrhoeal children reporting to four hospitals in the district of Kurunegala, Sri Lanka and from 121 controls with other diseases were investigated for enteric pathogens. All specimens were tested for Shigella spp, Salmonella spp and enteropathogenic Escherichia coli (EPEC). In addition, parasitic pathogens, heat labile enterotoxigenic Escherichia coli (ETEC LT), Campylobacter and rotavirus were sought among subsamples of the cases and controls. One or more pathogens were detected in the faecal specimens of 53.7% of the diarrhoeal children and 19.6% of the controls (P less than 0.001). Rotavirus was the most frequently identified pathogen. Cases (21.9%) were more likely to be positive for rotavirus than controls (6.5%) (p less than 0.05). Among children with diarrhoea the peak prevalence of rotavirus occurred in the 6-11 months age group. Shigella spp were the second most frequently isolated pathogens and the single most common cause of diarrhoea in children over two years of age. Again, cases (16.4%) were more likely to be infected than controls (1.7%) (p less than 0.001). Salmonella spp were isolated from 7.5% of diarrhoeal children and 3.3% of the controls (p greater than 0.10). Other pathogens had prevalence rates of less than 5%. Vomiting was associated with rotavirus diarrhoea (p less than 0.001), and fever with shigellosis (p = 0.02). In view of the different transmission routes and characteristics of the most important pathogens detected in this study it appears unlikely that a single environmental intervention can solve the public health problem posed by diarrhoeal diseases in Sri Lanka.
Shigellosis
Enterotoxigenic Escherichia coli
Sri lanka
Diarrhoeal disease
Enteropathogenic Escherichia coli
Cite
Citations (17)
Epidemic feature and bacteric etiological distribution for infectious diarrhea cases in Guiyang city
Objectives To explore the epidemic feature and etiological distribution for infectious diarrhea in Guiyang.Methods Epidemiological investigation of dirrheal patients from 6 surveillant hospital was done and stool specimens were collected during the period between June and December,2010.Salmonella,Aeromonas spp,Shigella,Campylobacter were tested by the isolation culture,biochemical identification and serotyping methods.Results In 434 patients,the ratio of male to female was 2.1:1,The high incidence age group was 0～(75.81%),and most patients occurred in the period from Julyy to October,the patient distribution was mainly concentrated in Nanming and Yunyan districts.Fourty-eight pathogenic bacteria strains were detected with the detection rate of 11.06%.Salmonella,Aeromonas spp were the most common pathogen,followed by Campylobacter jejuni,Shigella,Campylobacter coli.Salmonella Enteritidis and Salmonella Typhimurium were dominant serotypes among Salmonella,Shigella flexneri was the dominant serotype.The detection rate of pathogenic bacteria in 2-age group was the highest,accounting for 42.31%.The composition ratio of pathogenic bacteria of 0～ age group was the highest,accounting for 56.25%(27/48).The stool specimens were mainly watery stool,The detection rate of mucous stool was higher than loose and watery stool(??2 =30.89,P 0.005).Conclusions Infectious diarrhea in Guiyang had the following epidemic features:(1)high incidence age group was 0～age group;(2) most patients occurred in the period from July to October;(3) patient distribution were mainly concentrated in Nanming and Yunyan districts.(4)the main pathogenic bacteria causing infectious diarrhea in Guiyang are Salmonella,Aeromonas spp,Campylobacter jejuni,and Shigella respectively.We should take effective measures to prevent and control this desease for risk population.
Pathogenic bacteria
Etiology
Cite
Citations (0)
The clinical manifestations in 595 children hospitalized with gastroenteritis during a 15-month time frame were studied. They were divided into eight groups according to etiologic agent: rotavirus (203 patients); Salmonellae (98); Escherichia coli (55); Campylobacter (36); Shigella (22); combined rotavirus and salmonellae (44); combined rotavirus and other bacteria (26); and no pathogen (111). The mean duration of diarrhea was shortest in the rotavirus and "no pathogen" groups (4.8 and 5.6 days, respectively) and longest with pure and mixed salmonella infections (12.3 and 12.9 days, respectively). Associated manifestations were most frequent with salmonellae and least frequent with rotavirus and E. coli infections. Malnutrition also was most common with salmonellae and lowest with rotavirus and E. coli. There were no differences in the frequency of hypernatremia. Hyponatremia was most frequently encountered with salmonella (25% compared to 9% in the rest of the patients). Evidence of septicemia was found in 22 patients, 21 of whom were in the salmonella groups. The four deaths in this series (0.7%) also were in the salmonellae groups. The clinical severity of salmonella infection in developing countries, particularly in young and malnourished children, warrants attention to more intensive management. The selective use of antibiotics may help reduce the mortality and morbidity of gastroenteritis.
Acute gastroenteritis
Shigellosis
Cite
Citations (10)
To analyze the etiology and evolution of patients with acute gastroenteritis hospitalized in our pediatric department and to study the clinical and laboratory differences between acute viral and bacterial gastroenteritis.We studied the children with a diagnosis of acute gastroenteritis, aged between 0 and 14 years, who were consecutively admitted between 1987 and 2000. Differences were considered statistically significant if p < 0.05.A total of 2,613 patients diagnosed with acute gastroenteritis were hospitalized (10.4 % of hospital admissions). The most common pathogens isolated were rotaviruses (46.5 %), followed by Salmonella (32.6 %) and Campylobacter (19.3 %). Hospital admissions due to Salmonella (p < 0.0001), other bacteria (Escherichia coli and Shigella) (p < 0.002) and adenoviruses (p < 0.01) significantly decreased. Rotaviruses were the most frequently detected pathogens in winter and in children aged less than 1 year (p < 0.0001). The incidence of Salmonella spp was greater in summer and in children older than 2 years (p < 0.0001). The incidence of hyperthermia (rectal temperature higher than 38.5 degreeC) (p < 0.0001), dehydration (p < 0.0005) and fecal blood (p < 0.0001) was higher in bacterial diarrheas. Erythrocyte sedimentation rate (p < 0.001) and leukocyte counts were higher in bacterial gastroenteritis (p < 0.01).Rotaviruses were the most frequently isolated enteropathogens. The features that best distinguished between bacterial and viral diarrhea were hyperthermia and fecal blood. Hospital admissions due to Salmonella Shigella E. coli, and adenoviruses significantly decreased.
Etiology
Acute gastroenteritis
Cite
Citations (7)
Cite
Citations (0)
To determine the role of enteric pathogens in acute childhood diarrhoea in Guadeloupe, 161 children (108 cases and 53 controls) from 0 to 2 years of age, admitted to Pointe-à-Pitre/Abymes University Hospital, were evaluated over a five-month period. A known enteric pathogen was identified in 40.8% of children. The most commonly identified aetiologic agents were Salmonella (16.7% of cases), especially Haddar serotype and Rotavirus (20.5%). This virus was isolated more often in the dry season. Adenovirus were detected in 3.6% of diarrhoeal stools and were not significatively associated with diarrhoeal disease. No Shigella, Campylobacter or parasites were found.
Diarrhoeal disease
Acute gastroenteritis
Cite
Citations (2)
Etiology
Acute gastroenteritis
Acute diarrhea
Cite
Citations (1)
To determine the role of enteric pathogens in acute childhood diarrhoea in Hong Kong, 388 children with diarrhoea and 306 children of similar age without diarrhoea were evaluated in a hospital-based study during a one-year period from August 1994 to July 1995. Of the diarrhoeal cases, 55% were under 1 year and 95% were below 5 years of age. On admission, 22% had some dehydration but none was severely dehydrated. All children were well nourished. Oyer 60% of children with diarrhoea had one or more pathogens in their stool. Rotavirus was the most commonly isolated pathogen (34.6%), followed by Salmonella (23.3%), Campylobacter (4.7%) and Shigella (2.1%). Rotavirus was not assessed in the controls and was detected mainly during the winter months December to February. Bacterial pathogens were identified more commonly in diarrhoea patients (30%) than in controls (5.6%) (P < 0.001). Despite rapid recent socioeconomic development in Hong Kong, non-typhoidal Salmonella diarrhoea remains a significant local problem in infants under 1 year. Further detailed assessment of the transmission and prevention of this infection is required.
Etiology
Acute gastroenteritis
Diarrhoeal disease
Cite
Citations (26)
Over a 3-year period (from October 1981 to September 1984) 352 pediatric patients were treated for infectious diarrhea at the Division for Pediatric Infectious Diseases, Department of Pediatrics, University of Berne, Switzerland. Routine diagnostic tests on stool samples included cultures for Salmonella, Shigella, Campylobacter and Yersinia, and enzyme-linked immunosorbent assay (Rotazyme) for rotaviruses. In selected cases special tests for parasitic pathogens were also performed. The patients were divided into three etiologic groups to compare epidemiological, clinical and laboratory characteristics; group 1 = rotavirus, group 2 = no detectable pathogen, and group 3 = bacterial agents. Specific etiology of diarrhea was established in 210 of the 352 patients (59.5%). Rotaviral gastroenteritis represented the most common diagnosis (42.5%), whereas Salmonella was isolated from fecal cultures in 9% and Campylobacter jejuni in 3%. A parasitic etiology was documented in only 1%. In 5 patients two pathogens were recovered from stools: rotavirus and Salmonella in 4 cases and Salmonella and Campylobacter in 1 case. Relevant features of rotavirus, Salmonella and Campylobacter gastroenteritis in childhood are described in detail.
Etiology
Cite
Citations (1)