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    [Heredity, constitution and diathesis].
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    Diathesis
    Heredity
    Hemorrhagic diathesis
    A 19 year-old female, complaining of gigantic tumor on each breast and hemorrhagic diathesis, was admitted to our hospital. Laboratory data and clinical findings suggested the presence of DIC. Bilateral mastectomies reduced the bleeding tendency within a week. In conclusion, removal of the tumors was effective to avoid fatal hemorrhage.
    Hemorrhagic diathesis
    Diathesis
    Bleeding diathesis
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    Diathesis
    Heredity
    Hemorrhagic diathesis
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    An accurate diagnosis of the source of cerebral symptoms is necessary before instituting anticoagulation therapy for presumed cerebrovascular disease. In two cases the misidentification of the symptoms of brain abscesses as those of cerebrovascular disease led to the administration of anticoagulants and resulted in secondary, fatal intracerebral hemorrhage. It is necessary to differentiate factors involved in diagnosis and to be aware of the risks of anticoagulation therapy as well as the difficulty in clinical evaluation of a persistent bleeding diathesis (following such therapy).
    Brain abscess
    Hemorrhagic diathesis
    Diathesis
    Anticoagulant Therapy
    Bleeding diathesis
    A family with hereditary thrombopathic thrombocytopenia is described, with eight affected members in three generations. The haemorrhagic diathesis manifests itself by bleeding from mucous membranes and after operative procedures. The platelet count varies from 20,000 to 80,000 per cu.mm. The number of megakaryocytes in the bone marrow has been examined in two affected members, and the platelet survival in one, and both are normal. The thrombopathy consists in a deficiency of platelet factor 3 and in morphological anomalies. Electron microscopy has revealed a low content of α‐granules in platelets from two cases. The heredity shows an autosomal dominant pattern. A linkage of this genetic defect with blood group O seems probable.
    Bleeding diathesis
    Heredity
    Hemorrhagic diathesis
    There are diverse views concerning the so-called inherited tubercular diathesis; some even deny the existence of such a thing; others fully believe in it. Vogel is one of the latter. He regards heredity as an important etiologic factor in the production of infantile tuberculosis, because children born of parents affected with this disease develop it when exposed to bad hygienic surroundings. Baumgarten thinks there is a virus transmitted from parent to offspring. Bend is arrayed against him. Edward Squire of London from a study of 1,000 cases concludes that heredity accounts for 9 per cent, of cases among children born of phthisic parents, in excess of cases among children of non-phthisic parents. He therefore believes that heredity in these cases means simply a tendency to suffer from diseases, tuberculosis among others, which all children born of weakly parents have in common. Dr. Solomon Solis-Cohen says, "to make our conception of
    Heredity
    Diathesis
    Squire
    Hemorrhagic diathesis
    Etude de 100 cas. Recherche d'une predisposition familiale determinant l'âge auquel la maladie se manifeste. On constate de 81% des asthmatiques ont des antecedents familiaux de diathese allergique
    Diathesis
    Heredity
    Respiratory Hypersensitivity
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