Predictive value and relationship between intima-media thickness/carotid artery plaque score and severity of coronary artery disease
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Cardiologia CROATICA Objectives: The aim of this article is to investigate the relationship between the degree of the common carotid artery (CCA) atherosclerosis and the degree of complexity of the coronary artery disease (CAD) expressed with SYNTAX score. It is known that the existence of the CCA disease indicates with high probability the existence of CAD, but few studies have examined the relationship between CCA ultrasound findings and complexity, not just the presence of CAD. Patients and Methods: We included a total of 106 consecutive patients referred to the BH Heart Center for elective coronary angiography. In order to measure and calculate the mean intima-media thickness (IMT) we performed three measurements in predefined segments of CAA for both carotid arteries, the values are converged, and divided by the number of measurements. Plaque score (PS) was measured on the basis of maximum thickness of plaque in four clearly defined segments of both CCA. The final value of PS score is obtained by adding the thickness of plaques found in all segments of CCA. The complexity of coronary artery lesions is evaluated by using the SYNTAX score. The middle and high SYNTAX scores are associated with an increased risk of cardiac death and major cardiac events. Results: Data collection and statistical analysis is in progress and preliminary results indicate that IMT values and PS score significantly correlate with SYNTAX score >18 (r=.0,64, p 27 (r=.0,79, p<0,01). It is expected that final results will show that there is a significant correlation between the degree of CCA atherosclerosis measured by two methods — IMT and PS, and the degree of complexity of coronary artery lesions. Conclusion: Preliminary results show that carotid ultrasound examination has sufficient sensitivity and specificity in the detection of patients with high risk of significant CAD and it is an argument for broader use of CCA ultrasound for the evaluation of patients who are considered for coronary angiography. Besides, we are going to improve algorithm of patients selection for coronary angiography, so, our limited material and human resources and efforts will be directed towards the treatment of patients i.e. net clinical benefit will be improved.Keywords:
Intima-media thickness
Intima-media thickness
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Objective:To evaluate the relationship between common carotid artery (CCA) intima-media thickness (IMT), common carotid artery diameter (Dd) and carotid artery atherosclerosis (CAS) by ultrasonograph. Methods: The carotid arteries were assessed by PHILIPS IU22 color doppler ultrasonography in 40 patients with hypertension of high-risk group and 40 of mild dangerous group. IMT and Dd of common carotid arteries were measured in the two groups. Results: (1)The values of IMT and Dd were significantly higher in hypertensive patients of high-risk group than those of the mild dangerous group (P 0.05). (2)There were significant differences in isolated abnormal rates of IMT or Dd, and both IMT and Dd in hypertensive patients of high-risk group compared with those of mild dangerous group(P 0.05 or P 0.01). (3) After adjusting for age, gender, smoking and family history, the levels of blood pressure, blood glucose and blood fat still play an extremely positive role in the increasing of IMT and Dd. Conclusion: The enlargement of common carotid artery IMT and Dd was an objective marker to CAS, but coexistent abnormalities of IMT and Dd were more sensitive to CAS.
Intima-media thickness
Tunica intima
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Lipoprotein(a)
Value (mathematics)
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Objective To investigate the clinical value of automatic measurement of carotid intima-media thickness(CIMT) based on AHP.Methods The CIMT and vascular age(VA) of 238 healthy persons were obtained with ultrasound arterial health package.IMT of common carotid artery was measured manually.Results The CIMT of different positions were different(Bulbcommon carotid arteryinternal carotid artery,P0.05).The CIMT of the group whose age were older than sixty was significantly higher than that of other groups(P0.05).The VA increased with the CIMT thickening(P0.05) or the age increasing(P0.05).However,the VA was younger than the physical age in all groups(P0.05).The automatic measurement values were significantly smaller than the manual ones(P0.05).Conclusion The proposed method is accurate and convenient,and has potential to assess atherosclerosis in clinic.
Intima-media thickness
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Objectives To study the relationship between ambulatory pulse pressure(PP) and carotid artery intima-media thickness in elderly patients with essential hypertension. Methods The 24 hours ambulatory blood pressure monitoring was performed in a total of 103 elderly patients with essential hypertension. According to day-and night-time average PP,the patients were divided into two groups: PP60 mm Hg group and PP≥60 mm Hg group. The ultrasound technique was used to detect the carotid artery intima-media thickness. The comparison of difference of the carotid artery intima-media thickness and the correlative analysis of every parameter of the carotid artery intima-media thickness and PP in two groups was done. Results There was significantly different in the carotid artery intima-media thickness between PP60 mm Hg group and PP≥60mmHg group (P0.01). There was better correlation of PP and the carotid artery intima-media thickness,especially the correlation of nocturnal PP and the carotid artery intima-media thickness was the best. Conclusions The ambulatory PP (especially nocturnal PP) of the elderly patients with essential hypertension are the most important factors which influent the carotid artery intima-media thickness.
Intima-media thickness
Essential hypertension
Pulse pressure
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Intima-media thickness
Coronary atherosclerosis
Value (mathematics)
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Purpose: To measure the thickness of intima and media layers of carotid arteries of peri- and post-menopausal women using standard ultrasound equipment present in many Ob & Gyn departments.
Intima-media thickness
Peri
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Intima-media thickness
Carotid artery disease
Value (mathematics)
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