[Quantitation of left ventricular function after an inferior or superior myocardial infarct. Comparative value of resting ejection fractions or after effort].
0
Citation
0
Reference
10
Related Paper
Keywords:
Ventricular Function
Cite
Objective To study the relationship between the plasma level of B-type natriuretic peptide(BNP) and the left ventricular function in patients with coronary heart disease. Methods BNP levels in plasma of 30 nomal controls and 69 patients with coronary heart disease were measured by chemilumino-immunoassay. The ventricular function was measured by NYHA and colored doppler echocardiography. Results The BNP concentrations in control group, ventricular function (Ⅰ-Ⅱ) group and ventricular function (Ⅲ-Ⅳ) group were (31.56±21.48) μg/L, (105.52±(91.77)) μg/L and (433.18±378.03) μg/L respectively. There was statistical significance among these groups(P(0.001). The levels of plasma BNP and the left ventricular ejective fraction (LVEF) had a significant negative correlation (r=(-0.70), P0.001). BNP levels of LVEF≤40% subgroup were significantly higher than those of LVEF40% subgroup (P0.01). Conclusions BNP level reflects the left ventricular function in patients with coronary heart disease. The determination of BNP has important value in the diagnosis of early ventricular dysfunction and the evaluation of the severity of cardiac failure.
Ventricular Function
Brain natriuretic peptide
Cite
Citations (0)
Cite
Citations (14)
Objective To investigate the relationship plasma brain natriuretic peptide(BNP)level and left ventricular remodling(LVR) and ejection fraction(EF) after acute myocardial infarction.Methods BNP was determined in 21 acute myocardial infarction.Left ventricular diastolic diameter(LVDd) and.Left ventricular systolic diameter(LVDs) was measured in echocardiography and calculated left ventricular end diastolic volume(LVEDV) and left ventricular end systolic volume(LVESV)and EF.Results BNP was significantly high in 21 myocardial infarction and more significantly higher in LVR group(P0.01).BNP was positive relation with LVDd and LVEDV and LVESV(r=0.44,0.48,(0.62;)P0.05,0.05,0.01)and negative relation with EF(r=-0.64,P0.01).Conclusion BNP can be a simple and available sign in diaganosis and finding LVR.
Brain natriuretic peptide
End-diastolic volume
Ventricular Function
Cite
Citations (0)
Ventricular Function
Cite
Citations (17)
Objective To investigate the plassma levels of brain natriuretic peptide(BNP) and high-sensitivity C-reactive protein(hs-CRP) in patients with acute myocardial infarction(AMI),and estimate its value in the risk stratification.Methods The BNP and the serum levels of hs-CRP were detected in 128 cases with non-AMI and 120 cases with AMI.Left ventricular ejection fraction(LVEF) and left ventilator posterior wall thickness growing rate at systole(△T%) were measured by echocardiography.Results Compared with control group,AMI patients had high serum levels of hs-CRP.The higher the killip class was,the higher the levels of hs-CRP and BNP were.The concentration BNP and hs-CRP in AMI patients had a parallel rationship with LVEDD(P 0.05),but a nenative correlation with left ventricular ejection fraction(LVEF)(P 0.05).Conclusion The concentration of BNP and hs-CRP can help to evaluate the risk stratification and prognosis in patients with AMI.
Brain natriuretic peptide
Risk Stratification
Killip class
Cite
Citations (0)
Objective To evaluate the effects of different styles of coronary heart disease (CHD) and different regions of acute myocardial infarction (AMI), its risk factors and branches of coronary stenosis on left ventricular remodeling and systolic function by applying echocardiography. Methods 251 patients with CHD and 96 without CHD (NoCHD) were verified by coronary angiography. CHD patients were divided into SA (stable angina pectoris, n =26), UA (unstable angina pectoris, n =53), AMI ( n =140) and OMI (old myocardial infarct, n =30) based on cTnT, cardiac enzyme and ECG. AMI patients were further divided into subgroups including Aa (acute anterior myocardial infarct, n =53), Ai (acute inferior myocardial infarct, n =54) and Aa+Ai ( n =33) based on ECG. Cardiac parameters [IVSd (end diastolic interventricular septum thickness), LVd (end diastolic left ventricular internal diameter), LM (left ventricular mass), EDV (end diastolic left ventricular volume), ESV (end systolic left ventricular volume) and EF (left ventricular ejection fraction)] were measured by ACUSON 128XP/10 echocardiography. The effluence of the involved branches of coronary stenosis, blood pressure, blood lipids, glucose and etc on LVEF and LVd was analyzed in patients with AMI. Results EDV, ESV and EF in patient with AMI, OMI and UA were significantly changed ( P 0 05～0 0001), especially in those with AMI. LM was mainly increased in patients with OMI ( P 0 01) and LVd was mainly increased in patients with AMI. EF was significantly decreased and EDV, ESV, LM and LVd were remarkably increased in patients with Aa and Aa+Ai. With the multiple regression analysis by SPSS software, we found the branches of involved coronary stenosis and systolic blood pressure after AMI were negatively related to LVEF in patients with AMI, while there was no significant relationship between other factors and LVEF. LVEF was significantly decreased, and LVd and LM were remarkably increased in patients with hypertension before AMI, compared to patients without hypertension ( P 0 001). Conclusions Effects of different styles of CHD and different regions of AMI on left ventricular remodeling and cardiac function are different. Myocardial infarction is one of the most important causes of left ventricular remodeling and cardiac dysfunction, especially in AMI patients with Aa and Aa+Ai. Multiple vessel stenosis and systolic blood pressure mainly affected LVEF in patients with AMI, reduced LVEF. Antecedent hypertension might be a main reason of bringing about cardiac remodeling and dysfunction.
Interventricular septum
Ventricular remodeling
Cite
Citations (0)
The modern methods of treatment of acute myocardial infarction allow to avoid the early postinfarction remodelling but increase the number of patients with chronic heart failure and preserved systolic function of heart. According to the results of our study, the stiffness of the great arteries is increased among patients with chronic heart failure and preserved left ventricular ejection fraction, developed after myocardial infarction. In addition the severity of heart failure depends on the increase of pulse wave velocity. The positive correlations between increased stiffness of the great arteries and the levels of BNP and NTproBNP are determined among chronic heart failure patients with preserved left ventricular ejection fraction in one year after myocardial infarction.
Cite
Citations (0)
Objective To investigate the changes and significance of plasma visfatin level in patients with ST-segment elevation myocardial infarction(STEMI).Method Patients were divided three groups,including 23 patients with STEMI,38 patients with chronic angina and 19 patients with non-coronary heart disease.The examination content included coronary angiography,electrocardiogram,echocardiography,plasma visfatin,cardiac troponin I,myocardial enzyme,N-terminal pro-B-type brain natriuretic peptide(NT-proBNP),total white blood cells count,neutrophil count and monocyte count.The correlation between plasma visfatin level and relevant parameters such as cardiac troponin I,NT-proBNP,echocardiography and the number of diseased coronary arteries in STEMI patients was analyzed.Result Compared to the chronic angina and non-coronary heart disease patients,the levels of plasma visfatin were significantly elevated in acute STEMI patients.Increasing concentrations of visfatin were positively associated with cardiac troponin I,myocardial enzyme,NT-proBNP,total white blood cells count,neutrophil count and monocyte count,but were negatively associated with left ventricle ejection fraction and left ventricle end-systolic diameter(P0.05).The levels of plasma visfatin were significantly elevated in patients with multi-coronary arteries lesion compared with that of patients with single and double-coronary arteries lesion(P0.05).Conclusion The level of plasma visfatin may be significantly elevated in STEMI patients,which is closely related to biomarkers of myocardial damage,left ventricle ejection fraction and the number of diseased coronary arteries.
Coronary arteries
Unstable angina
Cite
Citations (0)
OBJECTIVE To study the association between the plasma concentration of brain natriuretic peptide and severity?left ventricular function?prognosis in patients with acute myocardial infarction(AMI). METHODS Sixty-three patients with acute myocardial infarction were enrolled in this study. The plasma concentration of BNP were measured at 24 hours after infarction. The infarction areas were measured according to the electrocardiogram. Left ventricular function was evaluated by echocardiography with the parameters of left ventricular ejection fraction (LVEF)after one week. Patients were followed up for three months,and their main adverse cardiac events (angina pectoris,sudden death et al) in patients of AMI were observed. RESULTS The concentration of BNP in patient with AMI was related with severity of the disease,the BNP increasd (P0.01),with the enlargement of infarction areas while with the decrease of LVEF,the BNP increased (P0.05). The development of any clinical main adverse cardiac events (depth/CHF/reinfarction) occurred more frequently in patients with a higher plasma BNP level(P=0.02). CONCLUSION Plasma concentration of BNP in patients with AMI might be a reliable biochemical marker for predicting the severity and prognosis of this disease.
Brain natriuretic peptide
Unstable angina
Cite
Citations (0)
Ventricular dyssynchrony
Cite
Citations (34)