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    Acetylated galactosamine is a receptor for the influenza C virus glycoprotein
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    An enzymatic method is described for distinguishing D-glucosamine from galactosamine. The method is based on the fact that glucosamine is phosphorylated by ATP in the presence of hexokinase, whereas galactosamine is not. Application of the procedure for the assay of biological preparations is illustrated by the demonstration of D-glucosamine in hydrolysates of a polysaccharide isolated from Shigella flexneri.
    Galactosamine
    Hexokinase
    Citations (20)
    Influenza virus particles bind rapidly to vesicular stomatitis, Sindbis, or Rauscher murine leukemia virus particles, forming mixed aggregates demonstrable by electron microscopy. The normal hemagglutinating property of influenza virus is inhibited by these viruses, providing a rapid quantitative assay. Prior treatment with neuraminidase blocks the ability of other viruses to inhibit influenza virus hemagglutination.
    Neuraminic acid
    Sindbis virus
    Hemagglutination assay
    Vesicular Stomatitis
    The influence of glucosamine, galactosamine, glucuronic acid and of some derivatives of these compounds on mucopolysaccharide metabolism and on protein metabolism of primary fibroblast monolayer cultures was studied. Glucosamine, glucosamine · HC1, glucosamine · HJ and glucosamine sulfate (in concentrations of 100 µg/ml each) caused a considerable, statistically highly significant increase of the secretion of mucopolysaccharides by the fibroblasts. N-Acetylglucosamine and N-acetylgalactosamine were effective too, though to a lesser degree. Glucuronic acid was without any influence on mucopolysaccharide production. The protein content of the cultures was not affected by the 7 compounds mentioned so far in concentrations of up to 100 µg/ml. Galactosamine and betaineglucuronate induced a certain depression of a mucopolysaccharide production and simultaneously a decrease of the cellular protein content.
    Galactosamine
    Uronic acid
    Hexosamines
    N-Acetylglucosamine
    Citations (50)
    There have been several reports of the incorporation of glucosamine into liver glycogen by an intraperitoneal injection of galactosamine, but it has not previously been considered that glucosamine is a normal component of liver glycogen. We now report that glucosamine occurs endogenously in rabbit- and pig-liver glycogens in the amount of about 1 nmol per 10 mg glycogen. Like the glucosamine incorporated by exogenous administration of galactosamine, the endogenous glucosamine takes the place of 1,4-linked alpha-glucose residues. It is found in both the outer and inner chains of the glycogen molecule.
    Galactosamine
    Glycogen branching enzyme