Amino acids composition and protein quality evaluation of marine species and meals for feed formulations in cephalopods

Tumor tissues are more likely to absorb amino acids from the body.At present,all types of amino acids used in clinical practice have obvious effects in promoting tumor growth.The amino acid imbalance will result in the overdose or deficiency of specific amino acids,both inhibiting the tumor growth and correcting the malnutrition.High-dose arginine inhibits the tumor growth; leucine boosts up the inhibitory effects of valine and improve the host's nutrition; the deficiency of methionine sensitizes the antineoplastics; the imbalanced valine has the most significantly antineoplastic effects; the decreased concentration of glutamine suppresses the tumor growth; glutamine and asparagine antagonist have been used in clinical trials due to their metabolic blockade of nuclear acids.Specific imbalanced amino acid regimens can effectively inhibite the proliferation of tumor and improve the nutritional status.

Essential amino acid

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Cationic amino acid transport in chicken small intestine

Comparative Biochemistry and Physiology Part A Physiology (1971)

Gene R. Herzberg Harland E. Sheerin Joseph Lerner

Cationic polymerization

10.1016/0300-9629(71)90163-0

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Citations (36)

The Amino Acids Required for Growth in Mice and the Availability of their Optical Isomers

Journal of Nutrition (1943)

Clifford D. Bauer Clarence P. Berg

Isoleucine

Amino acid synthesis

10.1093/jn/26.1.51

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Citations (73)

Amino acid composition and nutritional evaluation of different Hypsizygus marmoreus samples

Science and Technology of Food Industry (2016)

Wang Li Luo Hongxia Shurong Li Chi Quan-bo Huihua Wang

Essential amino acid

Complete protein

Glutamic acid

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Citations (1)

Postnatal amino acid uptake by the rat small intestine. Changes in membrane transport systems for amino acids associated with maturation of jejunal morphology.

PubMed (1979)

Seán Murphy Daniels Vg

The uptake of a number of amino acids by the developing small intestine of the rat was investigated in vitro. L-valine, L-leucine, L-methionine, L-phenylalanine, L-arginine and L-lysine were all taken up by active transport and concentrated within the jejunal mucosa. GABA was not actively transported by the jejunum. The kinetics of carrier transport of amino acids was determined from birth to maturity. The Michaelis constant (Km) of the L-leucine, L-methionine, L-arginine and l-lysine transport systems was found to be low postnatally and increased with age, particularly after the time of weaning. The rate of l-leucine, L-methionine, L-phenylalanine and L-lysine transport (Vmax) was high postnatally but decreased after weaning. Neutral amino acids were transported at higher rates than basic amino acids. l-arginine was poorly transported by the jejunum. The specificity of transport systems for amino acids was investigated in inhibition studies. Amino acid transport systems appeared to be polyfunctional in the postnatal period but were more specific in post-weaned animals. The changes in kinetics and specificity of amino acid transport in the small intestine are discussed with reference to their possible functional significance and to the maturational changes in the jejunum, particularly with the appearance of a functionally distinct absorptive cell lining the intestinal villi during the third postnatal week (the time of weaning).

Jejunum

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Citations (3)

Effect of Arginine upon the Toxicity of Excesses of Single Amino Acids in Chicks

Journal of Nutrition (1968)

Robert E. Smith

Isoleucine

Glutamic acid

Amino acid synthesis

10.1093/jn/95.4.547

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Citations (34)

Effect of amino acid imbalance on inhibition in tumor

Guoji zhongliuxue zazhi (2011)

Zhongfang Yan Wei Lu

The tumor patients always suffer from the serious metabolic disorder,and nutritional support for patient may improve the nutrition condition and meanwhile promote tumor growth.Application of amino acid imbalance solution,which may lead to the overdose or deficiency of some specific amino acid:arginine,leucine,methionine,valine,tyrosine,phenylalanine can contribute to improvement of patientk's nutritional condition and inhibition of tumor growth. Key words: Amino acids; Neoplasms; Nutritional support

Amino acid metabolism

10.3760/cma.j.issn.1673-422x.2011.03.010

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Nitrogen balance and body weight change of adult roosters fed single essential amino acid devoid diets.

Japanese poultry science (1985)

Jun‐ichi OKUMURA Yoshio Nakahiro Katsutoshi Kino

Diets completely devoid of single essential amino acid were fed to adult roosters for 7 days to investigate the effect on nitrogen balance and body weight change. Depending upon the kind of amino acid deprived from the diet the effects were different and the existence of the nutritional specificity of essential amino acid was confirmed. Among the essential amino acids tested, lysine, histidine and leucine had the least effect and threonine, arginine and methionine had the severest one. All other amino acids tested, tryptophan, glycine, phenylalanine and isoleucine, had medium effect of deficiency.

Isoleucine

Essential amino acid

Nitrogen balance

10.2141/jpsa.22.17

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Citations (9)