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    Leukocytosis and left shift associated with quinidine fever
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    Objective To investigate the clinical significance of leukocytosis. MethodsWith the analysis of blood test,we summed up the importance of white blood cell count(WBC) and the clinical significance of leukocytosis. ResultsWBC count was of high clinical value,to which clinicians could refer.Leukocytosis is mainly seen in infection and leukemoid reaction. Conclusions The result of WBC test,to a certain extent,determines the clinical diagnosis and treatment of leukocytosis.
    Leukocytosis
    Leukemoid reaction
    Clinical Significance
    White blood cell
    Citations (0)
    In this study we measured white blood cells count and haematoccrits of 300 subjects. The study was divided into two groups. Group A constituted the controls of 100 subjects with normal leukocyte counts. The group B  constituted the study group with a sample size of 200 subjects. The study group showed an elevated white blood cells count (leukocytosis). The average mean age of group A and B were   39±19 and 41±20 respectively.  The haematocrit was measured using the microhaematocrit method, whereas the white cell count was estimated using the manual Neubauer method.  The group A had a mean haematocrit and white cell count value of 35±8 and 7.1±1.6 respectively.  Whereas the group B had a mean haematocrit and white cell of 29±10 and 22.2±15.8 respectively. The results showed a significant decrease (p<0.05) in haematocrit of the study group (group B) as compared against the control group (group A) using student t test. This study had satisfied that a relationship do exist between haematocrit and leukocytosis. Hence, patients diagnosed of leucocytosis be placed on blood boosting therapy and diet to avoid anaemia. Keywords: Leukocytosis, haematocrit, anaemia, superoxide
    Leukocytosis
    White blood cell
    Group B
    Group A
    Citations (2)
    Acute abdominal symptoms in 162 children were investigated with rapidly quantified C-reactive protein (CRP), white blood cell (WBC) count and erythrocyte sedimentation rate (ESR) as laboratory parameters. When the symptoms had been present for at least 12 hours, the CRP level was greater than 10 mg/l in 72% of cases with histologic evidence of appendicitis, while leukocytosis (WBC greater than 15 000/mm3) and raised ESR (greater than 20 mm/l h) were found in 58% and 51%, respectively. If appendicitis had progressed to gangrenous stage, however, CRP alone was capable of identifying 83% of cases, while 76% had leukocytosis and 60% elevated ESR. When perforation had occurred there was greatly increased CRP and invariably leukocytosis, but elevated ESR in only 60%. With the combination CRP and WBC count (using rise in one or both), 88% of all appendicitis cases could be identified, and at least 96% of those with gangrene or perforation. The predictive value of combined positive CRP and WBC tests was not less than 93%.
    Leukocytosis
    Erythrocyte sedimentation rate
    White blood cell
    Perforation
    Citations (71)
    In 851 predominantly adult patients with septicaemia or endocarditis data regarding white blood cell (WBC) count, platelet count, ESR and C-reactive protein (CRP) obtained within 3 days of admission were analyzed retrospectively. Among 232 patients with complete laboratory data none had the combination of normal ESR, negative CRP and lack of both leukocytosis and thrombocytopenia. CRP was positive (>10 mg/l) in 93%, ESR was elevated (>20 mm/h) in 90%, leukocytosis (WBC>9×109/l) was present in 60% and thrombocytopenia (platelets<150×109/l) in 35% of the patients. Patients with pneumococcal infection had generally higher ESR and CRP values and WBC counts than patients with other infections.
    Leukocytosis
    White blood cell
    Erythrocyte sedimentation rate
    Bacteremia
    Blood cell
    Complete blood count
    Citations (17)
    Pseudohypoxemia has been reported in leukemic patients with extreme leukocytosis, and it is characterized by a low oxygen saturation on arterial blood gas analysis despite normal saturation on pulse oximetry. We report the case of a 51-year-old man with chronic lymphocytic leukemia and an elevated white blood cell (WBC) count after splenectomy, his progressive postoperative pseudohypoxemia gradually improved as the leukocytosis was lowered by chemotherapy. We believe this is the first report to show a statistically significant correlation between the WBC count and the degree of pseudohypoxemia in a patient with leukemia.
    Leukocytosis
    White blood cell
    Pulse Oximetry
    Oxygen Saturation