Surface modification of polydimethylsiloxane microchannel using air plasma for DNA capillary migration in polydimethylsiloxane–glass microfluidic devices
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Polydimethylsiloxane (PDMS) microchannel surfaces were modified by air plasma to improve their applicability in microfluidics. The procedure included an increase in air plasma duration from 10 to 30 s. This resulted in an increase of wettability which was demonstrated by the decrease of water contact angles from 105° to 8°. The surface modification‐assisted PDMS microchannel easily bonded to a glass surface, and a PDMS/glass microfluidic device was fabricated with a simplified process. Slight pressure applied directly over the PDMS microchannel (approximate dimensions of 2.5 µm deep and 8.8 µm wide) formed nanoslits with dimensions of 830 nm in width and 170 nm in height on the PDMS/glass interface. Nanoslit formation was directly correlated to the metastable collapse of PDMS microchannels on the glass surface after the plasma treatment. The fabricated microfluidic devices were successfully employed for λ ‐DNA capillary migration without any external driving force.Keywords:
Polydimethylsiloxane
Microchannel
Surface Modification
Compression applied to microfluidic chips in polydimethylsiloxane (PDMS) results in ordered surface crack patterns on oxidized microchannel boundaries with patterns showing variations with fluidic layout as well as material compliance.
Polydimethylsiloxane
Microchannel
Fluidics
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Arbitrary microchannel network was successfully produced with no costly equipment and no cytotoxic material. In our method, sacrificial caramel embedded inside solid PDMS (polydimethylsiloxane) simply dissolves to form arbitrary shaped enclosed channels. Deformation of caramel by its surface tension realizes cylinder microchannel easily.
Polydimethylsiloxane
Microchannel
Molding (decorative)
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Microchannel is not only a channel for fluid flowing,but also a tool for microfluid flow control. By incorporating the characteristics and feature of the microchannel,microfluid driving,sampling,mixing, separating droplets formatting and controlling have been realized.In recent years,most studies have been focused on the application of surface effects to achieve microfluid control,as the surface-to-volume ratio is nearly millionfold increased in microchannel relative to that in macrochannel and the surface effects are greatly increased in microfluidic flows.However,only a few studies were carried out on controlling microfluid flows by using microchannel structural characteristics.In order to illuminate the fact that the microchannel configuration is also an effective way to control microfluid flow behavior,this paper discusses two aspects of flow control based on microchannel configuration.One is a special configuration of microchanels to be used as microvalve,the other is a special microchannel configuration to be used for formatting and controlling tiny droplets.And thus microchannel configuration is shown to be able to play an important part in microfluidic control.
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Flow Control
Disk formatting
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In this research work, author has presented a short review on nanofluidics. Total three individual microchannel bends as microfluidic devices are designed, fabricated and tested in this experimental work using author’s own hands-on completely. Polymethylmethacrylate (PMMA) is the selected polymeric material to fabricate these microfluidic devices. Dyed water is prepared as working liquid to test these microfluidic devices. According to this experimental study, the surface-driven microfluidic flow of dyed water is faster in the microchannel of higher channel aspect ratio inside the microchannel bends. The surface-driven microfluidic flow of dyed water is faster due to the effect of centrifugal force inside the microchannel bends. This experimental work may be useful to develop the nanofluidic devices and systems in future by an experimental transition from microfluidics to nanofluidics.
Microchannel
Nanofluidics
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Microchannel
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We present a new method to generate droplets stored in cavity structures using microchannels containing grooves. We investigate the effects of flow rate and groove pitch microchannelondroplet size.
Microchannel
Polydimethylsiloxane
Groove (engineering)
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The polyimide based glass microfluidic devices are fabricated using the maskless lithography. Water is the only working liquid in this work. The effects of micropillar side length, microfluidic friction and surface area to volume ratio on the surface-driven capillary flow of water are studied experimentally. The surface-driven capillary flow of water is slower due to higher microfluidic friction. This work will be useful to control the water inside the microfluidic lab-on-a-chip systems for commercial applications. Cite this Article Subhadeep Mukhopadhyay. Experimental Studies on the Capillary Flow Phenomena in Polyimide Based Glass Microfluidic Devices. Emerging Trends in Chemical Engineering. 2017; 4(3): 22–26p.
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Preconcentration microfluidic devices are fabricated incorporating straight or convergent–divergent microchannels and hydrogel or N afion membranes. Sample preconcentration is achieved utilizing concentration–polarization effects. The effects of the microchannel geometry on the preconcentration intensity are systematically examined. It is shown that for the preconcentrator with the straight microchannel, the time required to achieve a satisfactory preconcentration intensity increases with an increasing channel depth. For the convergent–divergent microchannel, the preconcentration intensity increases with a reducing convergent channel width. Comparing the preconcentration performance of the two different microchannel configurations, it is found that for an equivalent width of the main microchannel, the concentration effect in the convergent–divergent microchannel is faster than that in the straight microchannel.
Microchannel
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Concentration polarization
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Polydimethylsiloxane
Microscale chemistry
Microreactor
PDMS stamp
Microchannel
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Polydimethylsiloxane (PDMS) microchannel surfaces were modified by air plasma to improve their applicability in microfluidics. The procedure included an increase in air plasma duration from 10 to 30 s. This resulted in an increase of wettability which was demonstrated by the decrease of water contact angles from 105° to 8°. The surface modification‐assisted PDMS microchannel easily bonded to a glass surface, and a PDMS/glass microfluidic device was fabricated with a simplified process. Slight pressure applied directly over the PDMS microchannel (approximate dimensions of 2.5 µm deep and 8.8 µm wide) formed nanoslits with dimensions of 830 nm in width and 170 nm in height on the PDMS/glass interface. Nanoslit formation was directly correlated to the metastable collapse of PDMS microchannels on the glass surface after the plasma treatment. The fabricated microfluidic devices were successfully employed for λ ‐DNA capillary migration without any external driving force.
Polydimethylsiloxane
Microchannel
Surface Modification
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Citations (4)