ГУМОРАЛЬНЫЕ ИММУНОЛОГИЧЕСКИЕ ПАРАМЕТРЫ У ДЕТЕЙ С ЮВЕНИЛЬНЫМ ИДИОПАТИЧЕСКИМ АРТРИТОМ И РЕАКТИВНЫМ АРТРИТОМ

The levels of humoral immunological parameters in children of 2-17 years old with oligoarticular juvenile idiopathic arthritis (n = 98), with reactive arthritis (n = 26) and conditionally healthy children (n = 42) were examined. There were no differences in the concentration of C-reactive protein and antibodies to modified citrullinated vimentin between healthy children and patients with joint diseases. The level of antibodies to extractable nuclear antigens and the antinuclear factor titer in children with juvenile arthritis were higher, than in healthy children and patients with reactive arthritis. The frequency of antibodies to extractable nuclear antigens and modified citrullinated vimentin in children with juvenile arthritis and reactive arthritis was low, most often an antinuclear factor in these patients was detected.