Specific IgE antibodies in brucellosis

Specific IgE antibodies and sensitization were assessed in patients with brucellosis in various forms. IgE antibodies were determined with enzyme immunoassay which demonstrated high specificity and sensitivity with conjugate against IgE antibodies in 509 serum samples. Specific IgE antibodies were present in most patients with acute, subacute or chronic brucellosis. Their synthesis seems to be a normal component of humoral immunity in response to brucellosis agent invasion. Allergy in brucellosis seems to arise without participation of the IgE antibodies as there is no correlation between the antibodies levels, the response to Burnet's allergic test and specific leukocytolysis activity.