The effect of hydrodissection with diclofenac sodium and nuclear rotation on prevention of posterior capsular opacity

Objective To investigate the safety and effectiveness of hydrodissection with diclofenac sodium and nuclear rotation on the prevention of posterior capsular opacity. Methods Seventy two patients ( 80 eyes) with age-related cataract were divided into four groups randomly and underwent phacoemulsification with IOL implantation. Hydrodissection was done with balanced salt solution in group A,with lidocaine in group B,with diclofenac sodium in group C,with diclofenac sodium and nuclear rotation in group D. Visual acuity,corneal endothelial cell density and grade of posterior capsular opacity were measured. Results There were no significant differences between four groups in the best corrected visual acuity and corneal endothelial cell densi-ty (P0.05). The PCO score of group C and D were lower than group A and D. Furthermore, the PCO score of group D was lower than group C. Conclusion Hydrodissection with diclofenac sodium and nuclear rotation is effective in preventing posterior capsular opacity and can be safely used in ophthalmic surgical practice. Key words: Phacoemulsification ;  Posterior capsular opacity ;  Diclofenac sodium ;