Downregulation of long non-coding RNA H19 promotes P19CL6 cells proliferation and inhibits apoptosis during late-stage cardiac differentiation via miR-19b-modulated Sox6

Yu Han,Hongdang Xu,Jiangtao Cheng,Yanwei Zhang,Chuanyu Gao,Taibing Fan,Bangtian Peng,Bin Li,Lin Liu,Zhaoyun Cheng

Downregulation of long non-coding RNA H19 promotes P19CL6 cells proliferation and inhibits apoptosis during late-stage cardiac differentiation via miR-19b-modulated Sox6

2016

Yu Han
Hongdang Xu
Jiangtao Cheng
Yanwei Zhang
Chuanyu Gao
Taibing Fan
Bangtian Peng
Bin Li
Lin Liu
Zhaoyun Cheng

Background Regulating cardiac differentiation to maintain normal heart development and function is very important. At present, biological functions of H19 in cardiac differentiation is not completely clear.

Keywords:

Biology
Cell biology
Stem cell
Apoptosis
Downregulation and upregulation
Normal heart
Proteomics
Long non-coding RNA
Gene knockdown
Cell cycle
GATA4
Cell growth
Gene

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