Increased gene expression levels of collagen receptor integrins are associated with decreased survival parameters in patients with advanced melanoma.

Expression of collagen receptor integrins α1β1 and α2β1 has been associated with progression and metastatic potential of malignant melanoma. Integrin α2β1 was originally characterized as a melanoma progression antigen. We have used real-time quantitative PCR to study the mRNA expression levels of th