Long-term cryopreserved autologous hematopoietic stem cells following azacytidine to successfully treat severe invasive pulmonary aspergillosis after therapy-related myelodysplastic syndrome and CD8+ T-cell autoimmune disorders: a case report.

ABSTRACT We describe the clinical case of a 57-year-old female with therapy-related myelodysplastic syndrome (t-MDS), occurring twelve years after being treated with cytotoxic agents for a follicular non-Hodgkin lymphoma (FL), whose course was complicated by autoimmune disorders (AIDs) and severe invasive pulmonary aspergillosis (IPA). Successful outcomes of IPA, AIDs and MDS were recorded with the infusion of long-term cryopreserved autologous hematopoietic stem cells (AHSC) following azacytidine.