Polylox barcoding reveals haematopoietic stem cell fates realized in vivo

Weike Pei,Thorsten B. Feyerabend,Jens Rössler,Xi Wang,Daniel Postrach,Katrin Busch,Immanuel Rode,Kay Klapproth,Nikolaus Dietlein,Claudia Quedenau,Wei Chen,Sascha Sauer,Stephan Wolf,Thomas Höfer,Hans-Reimer Rodewald

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo

2017

Weike Pei
Thorsten B. Feyerabend
Jens Rössler
Xi Wang
Daniel Postrach
Katrin Busch
Immanuel Rode
Kay Klapproth
Nikolaus Dietlein
Claudia Quedenau
Wei Chen
Sascha Sauer
Stephan Wolf
Thomas Höfer
Hans-Reimer Rodewald

An artificial recombination locus, Polylox, that can generate hundreds of thousands of individual barcodes is used to trace the fates of haematopoietic stem cells in mice.

Keywords:

In vivo
Locus (genetics)
Stem cell
Genetics
Haematopoiesis
Biology
Embryonic stem cell
Progenitor cell
Fate mapping
Cell biology
Stem cell marker
Transplantation

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

212

Citations