Experimental characterization of a high accuracy amperometric sense and control circuit for three-electrode biosensors

A Sense and Control Circuit (SCC) developed for amperometric concentration evaluation is redesigned, based on preliminary experimental investigations. This cost-effective circuit comprises a potentiostat for three-electrode electrochemical cell (biosensor) control and a transimpedance amplifier for cell current sensing. Stability, noise robustness and response time are improved, as demonstrated by experiments and simulations. SCC performances are evaluated in comparison with a professional system, by H2O2 concentration measurements.