Proinflammatory Effect of Endothelial Microparticles Is Mitochondria Mediated and Modulated Through MAPKAPK2 (MAPK-Activated Protein Kinase 2) Leading to Attenuation of Cardiac Hypertrophy

Dipti Tripathi,Bharti Biswas,Amit Manhas,A. P. Singh,Dipika Goyal,Matthias Gaestel,Kumaravelu Jagavelu

Proinflammatory Effect of Endothelial Microparticles Is Mitochondria Mediated and Modulated Through MAPKAPK2 (MAPK-Activated Protein Kinase 2) Leading to Attenuation of Cardiac Hypertrophy

2019

Dipti Tripathi
Bharti Biswas
Amit Manhas
A. P. Singh
Dipika Goyal
Matthias Gaestel
Kumaravelu Jagavelu

Objective— This study investigates the functional significance of mitochondria present in endothelial microparticles (EMP) and how MK2 (MAPKAPK2 [MAPK-activated protein kinase 2]) governs EMP produ...

Keywords:

Cell biology
MAPK-Activated Protein Kinase 2
Biochemistry
Proinflammatory cytokine
MAPKAPK2
Diabetes mellitus
Muscle hypertrophy
Biology
Mitochondrion
E-selectin
Protein kinase A
Monocyte
Cell culture
Oligomycin
Inflammation

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