[Mechanism research progress of tendon-derived stem cells in reconstruction of fibrocartilage zone at bone-tendon junction].

2017 
Objective: To summarize the mechanism research progress of tendon-derived stem cells (TDSCs) in the reconstruction of fibrocartilage zone at bone-tendon junction (BTJ). Methods: The domestic and abroad related literature about TDSCs in the reconstruction of fibrocartilage zone at BTJ was summarized and analyzed. 结果: TDSCs 具有向骨细胞、纤维软骨细胞及肌腱细胞分化的能力,因此具备形成纤维软骨带的潜能;决定 TDSCs 成骨、成软骨分化的因素有力学刺激、生物活性因子、细胞外基质及炎性因子等。. Conclusion: Because of the specificity of origin and location of TDSCs, TDSCs have the potential to be the seed cells for BTJ fibrocartilage zone repair. By applying external stimuli, TDSCs can be induced to form structures which are similar to fibrocartilage zone.
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