Efficacy of Mesenchymal Stem Cells in Suppression of Hepatocarcinorigenesis in Rats: Possible Role of Wnt Signaling

Mohamed Talaat Abdel Aziz,Mohamed F. El-Asmar,Hazem Atta,Soheir Mahfouz,H. Fouad,Nagwa Kamal Roshdy,Laila A. Rashed,Dina Sabry,Amira A. Hassouna,Fatma M. Taha

Efficacy of Mesenchymal Stem Cells in Suppression of Hepatocarcinorigenesis in Rats: Possible Role of Wnt Signaling

2011

Mohamed Talaat Abdel Aziz
Mohamed F. El-Asmar
Hazem Atta
Soheir Mahfouz
H. Fouad
Nagwa Kamal Roshdy
Laila A. Rashed
Dina Sabry
Amira A. Hassouna
Fatma M. Taha

Background The present study was conducted to evaluate the tumor suppressive effects of bone marrow derived mesenchymal stem cells (MSCs) in an experimental hepatocellular carcinoma (HCC) model in rats and to investigate the possible role of Wnt signaling in hepato-carcinogenesis.

Keywords:

Cancer research
Liver regeneration
Beta-catenin
Molecular biology
Mesenchymal stem cell
Bone marrow
Stem cell
Biology
Wnt signaling pathway
Cellular differentiation
Signal transduction
Cell
Survivin
Cell cycle
liver function

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