Abstract 13386: Extracellular Matrix Signaling in Marfan Syndrome Induced Pluripotent Stem Cell Derived Smooth Muscle Cells

Introduction: Mutation in the extracellular matrix (ECM) protein fibrillin-1 lead to aortic root aneurysm in Marfan Syndrome (MFS). ECM composition influences vascular smooth muscle cell (SMC) phen...