Advance in virulence factors of porcine Actinobacillus pleuropneumonia

Actinobacillus pleuropneumonia (APP) is an important contagious pathogen causing different age porcine infectious pleuropneumonia, and lead to severe economic loss to the swine industry. Some experiments demonstrate that various kinds of virulence factors have critical roles in complicated pathogenesis of APP.At present,vaccination is the best way for the prevention and control of this disease.Researching in subunit and genetic engineering vaccine of APP has practical value, and further studying of the characters of APP virulence factors is the base for this work.