Study on the quality standard of improvement of Tongluo-Zhujing pills

Objective To improve the quality standard of Tongluo-Zhujing pills. Methods We added the identification ofradix notoginseng andtypha orientalisby TLC and determination of the content of wedelolactone by HPLC. The study used Agilent ZORBAX SB-C18 (4.6 mm × 250 mm, 5 μm) column and the velocity of flow manufactured by the proper proportion was 1 ml/min. The detection wavelength was 249 nm . Results The new method could well identify radix notoginsengandtypha orientalis. The calibration curves of wedelolactone was in good linearity over the range of 0.064-0.642 μg (r=0.999 7) and the average recovery was 98.74% (RSD=1.61%). Conclusions The quality standard of Tongluo-Zhujing pills was proved effectively. Key words: Chromatography, thin layer; Chromatography, high pressure liquid; Quality control; Tongluo-Zhujing pills