Complement C4 induces regulatory T cells differentiation through dendritic cell in systemic lupus erythematosus

Hong-Bin Cheng,Rong-Yi Chen,Jing-Ping Wu,Li Chen,Yan-Hua Liang,Hai-Feng Pan,Zi-Feng Pan,Qing-Hua Zhang,Qing Li,Tian-Xi Du,Yongmei Lv,Jian-Qiang Shi

Complement C4 induces regulatory T cells differentiation through dendritic cell in systemic lupus erythematosus

2015

Hong-Bin Cheng
Rong-Yi Chen
Jing-Ping Wu
Li Chen
Yan-Hua Liang
Hai-Feng Pan
Zi-Feng Pan
Qing-Hua Zhang
Qing Li
Tian-Xi Du
Yongmei Lv
Jian-Qiang Shi

Background Systemic lupus erythematosus (SLE) is a prototypic systemic autoimmune disease. Complement component 4 (C4) has be proved to play a role in pathogenesis of SLE. In the present study, we investigated the effect of C4 on T cells differentiation.

Keywords:

Biology
Dendritic cell
Lupus erythematosus
Autoimmune disease
Immunology
Pathogenesis
Complement component 4
treg cell
systemic lupus
Regulatory T cell
healthy subjects
Stem cell

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