Insulin suppresses transcriptional activity of YAP in insulin target cells.

Samar Sayedyahossein,Andrew C. Hedman,David B. Sacks

Insulin suppresses transcriptional activity of YAP in insulin target cells.

2019

Samar Sayedyahossein
Andrew C. Hedman
David B. Sacks

An investigation into the effects of insulin on YAP in classic insulin target cells reveals that insulin increases YAP phosphorylation and reduces YAP-mediated transcription, providing a link betwe...

Keywords:

Insulin
Biology
Cell biology
G6PC
Phosphorylation
PCK1
Proximity ligation assay
Transcription factor
Hippo signaling pathway
Transcription (biology)

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