Arachidonic acid-producing polyketide synthase and its use

According to the present invention, beta-ketoacyl - acyl carrier protein synthase domain, malonyl-CoA: acyl carrier protein acyl transferase domain and an acyl carrier protein (. Hereinafter, ACP hereinafter) protein having a domain, a protein having ketoreductase domain, beta - ketoacyl -ACP synthase domain, chain length factor domain, an acyltransferase domain and FabA-like β- hydroxyacyl -ACP dehydratase protein having a domain, protein having enoyl ACP- reductase domain, and consists of proteins with phosphopantetheine transferase domain and it can provide a complex of the protein having an activity of producing ARA acetyl CoA as the starting substrate. Furthermore, include DNA encoding a protein constituting the complex of the protein, the biological activity of the complex of the protein is enhanced from the host organism, and other PUFA including the EPA or EPA with the organism method for efficiently producing no ARA-containing composition can be provided.