Association of ADIPOQ, leptin, LEPR, and resistin polymorphisms with obesity parameters in Hammam Sousse Sahloul Heart Study

BACKGROUND: Adipose tissue is an important endocrine organ that secretes a number of adipokines, such as adiponectin (ADIPOQ), leptin (LEP), leptin receptor (LEPR), and resistin (RETN) which may be implicated in obesity. Some adipokines' polymorphisms of genes might influence their concentrations and/or activities. Our aim was to study the relationship between seven SNPs in ADIPOQ (+45T

Keywords:

• Obesity
• Resistin
• Diabetes mellitus
• Leptin
• Medicine
• Population
• Leptin receptor
• Adipokine
• Molecular biology
• Single-nucleotide polymorphism
• Internal medicine
• Endocrinology
• Adiponectin

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