Sprayed in-situ synthesis of Polyvinyl alcohol/Chitosan loaded Silver nanocomposite hydrogel for improved antibacterial effects

Abstract To overcome the practical limitations of hydrogel preparations, applications and strength-based problems, the present study utilizes the use of sprayers for preparing polyvinyl alcohol/chitosan (PVA/CH) hydrogels. The particle size, morphology, stability, release studies and antibacterial activity of silver nanoparticles (AgNPs) had been studied. The particle size of AgNPs was found to be in the range of 4.59-10 nm (75 °C) with a polydispersity index (PDI) of 0.84. The morphological images exhibited inter-connecting porous structure with pore size in submicron’s (