Sulfonamides as selective oestrogen receptor β agonists
2011
Abstract A series of p -hydroxybenzenesulphonamides ERβ receptor agonists were discovered and several compounds identified had excellent selectivity over the related ERα receptor. One of these, compound 11 , had an interesting binding conformation determined by X-ray and represents an excellent starting point in the quest for further selective ERβ agonists.
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