Process for producing a transplant for reproduction hair TsutsumiHara group coat color is controlled, a composition comprising a reproduction hair TsutsumiHara group for the implant, and method of implantation

Disclosed is a technique to regenerate hair by transplantation of hair TsutsumiHara group, and an object thereof is to control the coat color to be reproduced. A method of manufacturing a graft for reproduction hair TsutsumiHara group coat color is controlled for hair growth occurring after implantation, the step of preparing the first cell mass containing the mesenchymal cells, epithelial cells preparing a second cell mass comprising the step of preparing a cell mass containing a dye stem cells, in at least one of the first cell mass and the second cell mass, cells containing the pigment stem cell step of binding the assembly, and, subsequently, a second cell mass and the first cell mass, at least one of said first bound to cell aggregates comprising said pigment stem cell It is brought into close contact with cell aggregates of said second cell mass to provide a production method comprising the step of culturing inside support. .BACKGROUND