Biosensing on a Chip: Study of Plasmonic Nanostructures Integrated in Microfluidic Devices

Arrays of plasmonic nanocavities with very low volumes, down to λ3/1000, have been fabricated by soft UV nanoimprint lithography. It leads to high refractive index sensitivity (368 nm/RIU) and figure of merit (∼46) and offers new perspectives for efficient biosensing experiments in ultralow volumes.