Mutational analysis of putative phosphate- and proton-binding sites in the Saccharomyces cerevisiae Pho84 phosphate:H+ transceptor and its effect on signalling to the PKA and PHO pathways

Dieter R. Samyn,Lorena Ruiz-Pavon,Michael R. Andersson,Yulia Popova,Johan M. Thevelein,Bengt L. Persson

Mutational analysis of putative phosphate- and proton-binding sites in the Saccharomyces cerevisiae Pho84 phosphate:H+ transceptor and its effect on signalling to the PKA and PHO pathways

2012

Dieter R. Samyn
Lorena Ruiz-Pavon
Michael R. Andersson
Yulia Popova
Johan M. Thevelein
Bengt L. Persson

In Saccharomyces cerevisiae, the Pho84 phosphate transporter acts as the main provider of phosphate to the cell using a proton symport mechanism, but also mediates rapid activation of the PKA (prot ...

Keywords:

Proton binding
Cell
Symporter
Biochemistry
Saccharomyces cerevisiae
Transporter
Phosphate
Signalling
Biology
Permease
Mutagenesis
Mutant
Protein kinase A

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