Lumbar bone mineral density in renal transplant patients on neoral and tacrolimus: a four-year prospective study.

Background.This prospective study was designed to investigate the long-term evolution of bone mineral density (BMD) in kidney transplant recipients.Methods.In 86 patients with functioning grafts, 65 on tacrolimus-based immunosuppression and 21 on cyclosporine-based immunosuppression, laboratory para