Past achievements, current status and future perspectives of studies on 3-hydroxy-3-methylglutaryl-CoA synthase (HMGS) in the mevalonate (MVA) pathway

Pan Liao,Hui Wang,Andréa Hemmerlin,Dinesh A. Nagegowda,Thomas J. Bach,Mingfu Wang,Mee-Len Chye

Past achievements, current status and future perspectives of studies on 3-hydroxy-3-methylglutaryl-CoA synthase (HMGS) in the mevalonate (MVA) pathway

2014

Pan Liao
Hui Wang
Andréa Hemmerlin
Dinesh A. Nagegowda
Thomas J. Bach
Mingfu Wang
Mee-Len Chye

Key message HMGS functions in phytosterol biosynthesis, development and stress responses. F-244 could specifically-inhibit HMGS in tobacco BY-2 cells and Brassica seedlings. An update on HMGS from higher plants is presented.

Keywords:

Acetoacetyl-CoA
Brassinosteroid
Botany
Acetyl-CoA
HMG-CoA reductase
Phytosterol
ATP synthase
Biosynthesis
Biology
Biochemistry
Sterol
plant biochemistry
Sequence homology

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