Stem Cell Proteomics

Recent advances in stem cell and proteomic technology carry tremendous potential to impact our understanding of mechanistic underpinnings and fundamental pathophysiology of cardiovascular disease. In this chapter, we introduce investigators new to these disciplines to the various types of stem cells relevant to cardiovascular biology and how, when combined with state-of-the-art proteomic analyses, they may be exploited for mechanistic and translational studies related to cardiomyopathies, coronary atherosclerotic disease, and heart failure. Although the potential of these emerging technologies is just beginning to be explored, this chapter aims to illustrate how integration of novel stem cell and proteomic technologies is poised to make significant contributions to future advanced therapies and diagnostics in cardiovascular medicine.