Multidrug-resistant Gram-positive bacteria antibacterial agent and a topical agent

Providing an external preparation containing multi-drug resistant Gram-positive bacteria antibacterial and it contains as an active ingredient a new component that is not impart resistance to multidrug bacteria. Multidrug-resistant Gram-positive bacteria antibacterial agent of the present invention is greater than HLB value is 9.5, 20 or less, containing an amphiphilic compound having an acyl group as an active ingredient. Further, the external preparation of the present invention comprises the multi-drug resistant Gram-positive bacteria antibacterial agent.