Enzymatic Plasmonic Engineering of Ag/Au Bimetallic Nanoshells and Their Use for Sensitive Optical Glucose Sensing

Enzyme works for plasmonic nanostructure: An interesting enzyme-responsive hybrid Ag/Au-GOx bimetallic nanoshell (NS) system is reported, in which control over the enzyme reaction of glucose oxidase (GOx) can automatically fine-tune the morphology (from complete NS to porous NS) and optical properties of the hybrid nanostructure. The phenomenon is further exploited as a new platform for sensitive optical glucose sensing.