Hypoxia-Induced TPM2 Methylation is Associated with Chemoresistance and Poor Prognosis in Breast Cancer

Jinfeng Zhang,Jian Zhang,Shouping Xu,Xianyu Zhang,Peiyuan Wang,Hao Wu,Bingshu Xia,Guangwen Zhang,Bo Lei,Lin Wan,Dekai Zhang,Da Pang

Hypoxia-Induced TPM2 Methylation is Associated with Chemoresistance and Poor Prognosis in Breast Cancer

2018

Jinfeng Zhang
Jian Zhang
Shouping Xu
Xianyu Zhang
Peiyuan Wang
Hao Wu
Bingshu Xia
Guangwen Zhang
Bo Lei
Lin Wan
Dekai Zhang
Da Pang

Background/Aims: Tropomyosin-2 (TPM2) plays important roles in functions of the cytoskeleton, such as cytokinesis, vesicle transport, cell proliferation, migratio

Keywords:

Methylation
Breast cancer
Cytoskeleton
Biochemistry
Vesicular transport protein
TPM2
Hypoxia (medical)
Cancer research
Cell growth
Cytokinesis
Biology
Paclitaxel
Bisulfite sequencing
Gene knockdown
MMP2
Chemotherapy
Cell

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