Robust neutralization assay based on SARS-CoV-2 S-protein-bearing vesicular stomatitis virus (VSV) pseudovirus and ACE2-overexpressing BHK21 cells.

Hua-Long Xiong,Yangtao Wu,Jia Li Cao,Ren Yang,Yingxia Liu,Jian Ma,Xiao-Yang Qiao,Xiang-Yang Yao,Baohui Zhang,Yali Zhang,Wangheng Hou,Yang Shi,Jing-Jing Xu,Liang Zhang,Shaojuan Wang,Baorong Fu,Ting Yang,Shengxiang Ge,Jun Zhang,Quan Yuan,Baoying Huang,Zhiyong Li,Tianying Zhang,Ningshao Xia

Robust neutralization assay based on SARS-CoV-2 S-protein-bearing vesicular stomatitis virus (VSV) pseudovirus and ACE2-overexpressing BHK21 cells.

2020

The global pandemic of coronavirus disease 2019 (COVID-19) is a disaster for human society. A convenient and reliable neutralization assay is very important for the development of vaccines and nove...

Keywords:

Ligand (biochemistry)
Wild type
Virology
Chemistry
Amino acid
Vesicular stomatitis virus
severe acute respiratory syndrome coronavirus 2
Monoclonal antibody
Titer
Neutralization

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