Permeability of Exendin-4-Loaded Chitosan Nanoparticles across MDCK Cell Monolayers and Rat Small Intestine

Mengshu Wang,a,# Yong Zhang,a,b,# Bingxue Sun,a Yanan Sun,a Xin Gong,a Yongge Wu,a Xizhen Zhang,a Wei Kong,*,a,b and Yan Chen*,a,b a National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University; and b Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, School of Life Sciences, Jilin University; Changchun 130012, China. Received July 26, 2013; accepted February 16, 2014