Cell sheet and manufacturing method thereof hyaluronic acid producing ability

For example, in a state of enhanced stem cell content, the polymer hydration force varies on a coated cell culture support to the surface in a temperature range of 0 to 80 ° C., the cells with hydration force is weak temperature range of the polymer cultured, then the culture fluid by the cells cultured by changing the temperature of the hydration force of the polymer becomes strong state is peeled off in sheet form, to be capable of obtaining high cell sheet of hyaluronic acid-producing ability Become.