Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes.

We thank the UCL Cancer Institute Genomics and Genome Engineering Core Facility (supported by the Cancer Research UK – UCL Centre), for providing access to the RainDance Thunderstorm platform, which was purchased on a Wellcome multi-user grant (99148). This work was primarily supported by grants from the Wellcome (grant 091182 to A.G., G.McV. and A.O.M.W.; grant 102731 to A.O.M.W. and studentship 105361 to H.K.R.), the Simons Foundation (332759 to A.G.) and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre Programme (to A.G.). S.B., P.D. and S.H.S. were supported by a Wellcome programme grant and D.S.P. was supported by EU-FP7. We acknowledge funding from the Medical Research Council (MRC) through the WIMM Strategic Alliance (G0902418 and MC_UU_12025) and the support of the High-Throughput Genomics core facility by the Wellcome grant 090532.