Multiple sclerosis and nephrotic syndrome in minimal change disease

The coinciding suffering of two or more autoimmune diseases has been occasionally reported during the last years. We report a multiple sclerosis case in a young male patient who presented minimal-change nephrotic syndrome with frequent relapses seven months later. New relapses have been prevented with cyclosporine therapy in a dose of 3,8 mg/kg bw/day associated to prednisone 10 mg/day during eighteen months. Documentation and investigation of such cases will help to the best understanding of the immunopathogenesis of those diseases.