Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure

Stephan R. Lederer,Nicole Friedrich,Rudolf Gruber,R. Landgraf,Marcel Toepfer,Thomas Sitter

Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure

2004

Stephan R. Lederer
Nicole Friedrich
Rudolf Gruber
R. Landgraf
Marcel Toepfer
Thomas Sitter

Background: The CD40-CD40L (CD154) costimulatory pathway plays a critical role in the pathogenesis of kidney allograft rejection. In renal transplant biopsies, CD4+CD40L+ graft-infi

Keywords:

Chronic allograft nephropathy
Immunology
Renal function
Whole blood
CD40
Ex vivo
CD154
Pathology
Kidney
Flow cytometry
Medicine
Pathogenesis

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