Oxylipins from Dracontium loretense

Four novel oxylipins (1−4) were isolated from the n-butanol extract of the corms of Dracontium loretense. Their structures were assigned by 1D and 2D NMR analyses and electrospray ionization multistage ion trap mass spectrometry (ESI-ITMSn) data. Relative configurations were assigned on the basis of combined analysis of homonuclear and heteronuclear 2,3J couplings, along with ROE data. Oxylipin 2 exhibited an immunostimulatory effect on human PBMC proliferation.