MIF/CD74 axis is a target for novel therapies in colon carcinomatosis

Fabio Bozzi,Angela Mogavero,Luca Varinelli,Antonino Belfiore,Giacomo Manenti,Claudio Caccia,Chiara C. Volpi,Galina V. Beznoussenko,Massimo Milione,Valerio Leoni,Annunziata Gloghini,Alexandre A. Mironov,Ermanno Leo,Silvana Pilotti,Marco A. Pierotti,Italia Bongarzone,Manuela Gariboldi

MIF/CD74 axis is a target for novel therapies in colon carcinomatosis

2017

Fabio Bozzi
Angela Mogavero
Luca Varinelli
Antonino Belfiore
Giacomo Manenti
Claudio Caccia
Chiara C. Volpi
Galina V. Beznoussenko
Massimo Milione
Valerio Leoni
Annunziata Gloghini
Alexandre A. Mironov
Ermanno Leo
Silvana Pilotti
Marco A. Pierotti
Italia Bongarzone
Manuela Gariboldi

Background Strategies aimed at obtaining a complete cytoreduction are needed to improve long-term survival for patients with colorectal cancer peritoneal carcinomatosis (CRC-pc).

Keywords:

Cancer research
Metformin
Biology
Colorectal cancer
AMPK
Immunology
Macrophage migration inhibitory factor
CD74
Ribosomal protein s6
Stem cell marker
Cancer stem cell
LGR5
Mitochondrial respiratory chain complex I
Organoid
Medicine

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