Indikation und Anwendung der ketogenen Diät im Kindesalter1. Workshop ketogene Diät am 15. Dezember 2000 in Essen

The ketogenic diet, a high fat, low carbohydrate diet, is the treatment of choice for pyruvate-dehydrogenase-deficiency and GLUT1 deficiency syndrome, and effective in intractable childhood epilepsy. In Germany the diet is hardly used, protocols are not standardized, and German literature is non-existent. 12/2000 physicians and dietitians using the ketogenic diet in Germany met.In 52 patients a good response was seen in pyruvate-dehydrogenase-deficiency (n = 7) and GLUT1 deficiency syndrome (n = 9). In intractable childhood epilepsy (n = 36) the effect of the ketogenic diet was rated as good in 3 patients (8%), moderate in 14 patients (39%), and poor in 19 patients (53%). Compliance was good and few side effects were observed. Standards for the introduction and maintenance of the ketogenic diet were developed and protocols coordinated to ensure quality control and a prospective evaluation of the diet.