The Transcription Factor FOXA2 Suppresses Gastric Tumorigenesis In Vitro and In Vivo

Background and Aims The transcription factor forkhead box A2 (FOXA2) plays a central role in the development of endoderm-derived organs. It has been reported that FOXA2 acts as a suppressor in many kinds of tumor. However, little is known about the role of FOXA2 in gastric cancer.