Synthesis of 1-Substituted-phytosphingosine : Novel Protection of Phytosphingosine

Medicinal Science Division, Korea Research Institute of Chemical Technology, P.O. Box 107, Yusong, Daejeon 305-600, KoreaReceived December 13, 2002Key Words : Phytosphingosine, 1-Substituted-phytosphingosine, Phytosphingosine 1-phosphate, Sphin-gosine, Cyclic carbonatePhytosphingosine, one of the major sphingosine deriva-tives was found in microorganisms, yeast, plants, and fungias a major membrane component, and also found in manymammalian tissues